Margaret Colonna (13th century – September 20, 1284) was a member of the Colonna family, beatified by the Catholic church.
Born in Rome, her parents died there when she was still a young girl, and she was left to the care of her two brothers, the youngest of whom was raised to the cardinalate by Pope Nicholas III in 1278. Having resolutely refused the proposal of marriage made to her by the chief magistrate of Rome, she retired to a lonely retreat near Palestrina where she passed her time in practices of piety and penance. Her charity towards the poor was unbounded, and she was thought to be miraculously rewarded. Through the influence of her brother, Cardinal Colonna, Margaret obtained the canonical erection of a community of Urbanist Poor Clares at Palestrina, of which she most probably became superioress. Seven years before her death, she was afflicted with an ulcer.
This article incorporates text from a publication now in the public domain: Herbermann, Charles, ed (1913). "Blessed Margaret Colona". Catholic Encyclopedia. Robert Appleton Company.